3-D Super-Resolution Ultrasound (SR-US) Imaging with a 2-D Sparse Array

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Title: 3-D Super-Resolution Ultrasound (SR-US) Imaging with a 2-D Sparse Array
Authors: Harput, S
Christensen-Jeffries, K
Ramalli, A
Brown, J
Zhu, J
Zhang, G
Leow, CH
Toulemonde, M
Boni, E
Tortoli, P
Eckersley, RJ
Dunsby, C
Tang, M-X
Item Type: Working Paper
Abstract: High frame rate 3-D ultrasound imaging technology combined with super-resolution processing method can visualize 3-D microvascular structures by overcoming the diffraction limited resolution in every spatial direction. However, 3-D super-resolution ultrasound imaging using a full 2-D array requires a system with large number of independent channels, the design of which might be impractical due to the high cost, complexity, and volume of data produced. In this study, a 2-D sparse array was designed and fabricated with 512 elements chosen from a density-tapered 2-D spiral layout. High frame rate volumetric imaging was performed using two synchronized ULA-OP 256 research scanners. Volumetric images were constructed by coherently compounding 9-angle plane waves acquired in 3 milliseconds at a pulse repetition frequency of 3000 Hz. To allow microbubbles sufficient time to move between consequent compounded volumetric frames, a 7-millisecond delay was introduced after each volume acquisition. This reduced the effective volume acquisition speed to 100 Hz and the total acquired data size by 3.3-fold. Localization-based 3-D super-resolution images of two touching sub-wavelength tubes were generated from 6000 volumes acquired in 60 seconds. In conclusion, this work demonstrates the feasibility of 3D super-resolution imaging and super-resolved velocity mapping using a customized 2D sparse array transducer.
Issue Date: 5-Feb-2019
URI: http://hdl.handle.net/10044/1/71487
Sponsor/Funder: Engineering & Physical Science Research Council (EPSRC)
Funder's Grant Number: EP/N015487/1
Keywords: physics.med-ph
Appears in Collections:Faculty of Engineering
Bioengineering



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